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RESEARCH ARTICLE
Year : 2016  |  Volume : 15  |  Issue : 1  |  Page : 80-83

High -sensitivity c-reactive protein in hypertensive patients living in United Arab Emirates


Correspondence Address:
Abbas AL-Sharifi
Prof. of Cardiology and Internal Medicine, Department of Internal Medicine, College of Medicine, Al-Mustansiriya University

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Source of Support: None, Conflict of Interest: None


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Background: Inflammation has been found to correlate with endothelial dysfunction and relate to renin-angiotensin system, as a result it has hypothesized that hypertension may be in part an inflammatory disorder. High-sensitivity C- reactive protein (Hs-CRP) is an independent predictor of future cardiovascular events and it predicts risk of incident hypertension. Objectives: of this study is to determine the relationship of the Hs-CRP, a marker of systemic inflammation, with hypertension in hypertensive patients living in United Arabic Emirates. Patients & Methods: This study was conducted in, Dubai between May 2008 and April 2009. 86 patients with hypertension and 84 healthy individuals were included in this study. Hs-CRP and lipid profile; Total cholesterol (TC). Triglyceride (TG), Low density lipoprotein (LDL),and High density lipoprotein (HDL) were measured for both groups. Results: Hs-CRP levels were higher in hypertensive patients than in control, but this difference was not statistically significant (p=0.217). Frequency of low and high risk levels was significantly higher in hypertensive patients than in control (p=0.003), while at average risk levels frequency was higher in control individuals than in patients (p=0.003). Overall there was positive association between increasing levels of Hs-CRP and risk of developing hypertension. There was no significant correlation between Hs-CRP and BMI, (r=0.6, p=0.447). SBP (r=0.0.197; p=0.139) and DBP (r=0.112, p=0.455). Conclusionin: High s-CRP is an independent risk factor for hypertension, so it is recommended to be done as part of strategies of global risk assessment.


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