• Users Online: 48
  • Print this page
  • Email this page
Year : 2022  |  Volume : 21  |  Issue : 1  |  Page : 53-58

Pediatric rhabdomyosarcoma in child's central teaching hospital: An eight-year experience

Department of Heamato-Oncology, Child's Central Teaching Hospital, Baghdad, Iraq

Correspondence Address:
Dr. Shaimaa Saad Abdul-Zahra AL-Harris
MBCHB, Pediatric Specialist, FICMS- CABP (Ped), Pediatric Hemato-Oncologist, Department of Hemato-Oncology, Childs Central Teaching Hospital, Baghdad
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/mj.mj_25_21

Rights and Permissions

Background: Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in the first two decades of life. There is, however, a paucity of reports on the pattern of its occurrence in Iraq. Aim: To determine the demographic characteristics, clinical presentation, and survival among children with RMS treated at Child's Central Teaching Hospital (CCTH). Patients and Methods: A retrospective study was on 48 patients of histologically proven. RMS, in previously untreated children aged <15 years old at the CCTH in Baghdad, during the period from January 2009 to December, 2017. Results: Forty-eight patients with confirmed RMS were included. The mean age (standard deviation) was 4.9 (3.5) years. Thirty-four patients (70.8%) were <6 years, male 22 patients (46.8%), female 26 patients (54.2%), male:female ratio of approximately 1:1.2. Histopathology was embryonal in 38 case (79.1%). Incisional biopsy was done in 21 patients (43.8%), while excisional biopsy in 18 (37.5%) patients. The head and neck was the most common site of involvement at presentation, (nonorbital) 16 (33.3%) of cases. The estimated 4-year event-free survival (EFS) was 26.3% ± 7%. Twenty-one (43.8%) patients abandoned treatment. Among the cases who completed their treatment in the center, eight cases (16.7%) relapsed. In univariate analysis using log-rank test, nodal involvement was found to significantly influence the EFS at 4 years (P = 0.01). The estimated 4-year overall survival was 41.4% ± 9%. Nodal involvement significantly reduces overall survival at 4 years (P = 0.006). Conclusions: Clinical features and epidemiology of RMS in Iraqi children treated at CCTH somewhat resembles those of other countries. However, the EFS at 4 years and overall survival at 4-years are lower than that reported elsewhere.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded41    
    Comments [Add]    

Recommend this journal